Ontology highlight
ABSTRACT:
SUBMITTER: Teng Q
PROVIDER: S-EPMC6657412 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Chemical science 20190613 28
A rhodium-catalyzed highly regio- and enantioselective hydroalkynylation, generating <i>cis</i>-hydrobenzofuranone-tethered enynes has been developed. The reaction proceeds with a selective head-to-head insertion and symmetry breaking Michael addition cascade. One product was produced from tens of possible isomers through precise control of chemo-, regio-, and stereoselectivities using a single rhodium catalyst. Notable features of this method include 100% atom-economy, mild reaction conditions ...[more]