Ontology highlight
ABSTRACT:
SUBMITTER: Ouhammouch M
PROVIDER: S-EPMC154304 | biostudies-literature | 2003 Apr
REPOSITORIES: biostudies-literature
Ouhammouch Mohamed M Dewhurst Robert E RE Hausner Winfried W Thomm Michael M Geiduschek E Peter EP
Proceedings of the National Academy of Sciences of the United States of America 20030411 9
The hyperthermophilic archaeon Methanococcus jannaschii encodes two putative transcription regulators, Ptr1 and Ptr2, that are members of the Lrp/AsnC family of bacterial transcription regulators. In contrast, this archaeon's RNA polymerase and core transcription factors are of eukaryotic type. Using the M. jannaschii high-temperature in vitro transcription system, we show that Ptr2 is a potent transcriptional activator, and that it conveys its stimulatory effects on its cognate eukaryal-type tr ...[more]