Ontology highlight
ABSTRACT:
SUBMITTER: Abad R
PROVIDER: S-EPMC1595317 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Abad R R Alcalá B B Salcedo C C Enríquez R R Uría M J MJ Diez P P Vázquez J A JA
Clinical and vaccine immunology : CVI 20061001 10
Variations in class 2/3 (PorB) proteins form the basis for meningococcal serotyping. Antibodies against these proteins are bactericidal, making serotyping results useful not only for epidemiological surveillance of meningococcal disease but also for identifying potential vaccine components. A total of 20 to 60% of meningococcal B and C isolates from any given population are nontypeable (NT) using a panel of monoclonal antibodies. To analyze the mechanisms responsible for the nonserotypeability c ...[more]