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Heterogeneity of the PorB protein in serotype 22 Neisseria meningitidis.


ABSTRACT: The genetic diversity of porB genes from meningococcal isolates characterized as serotype 22 was investigated by gene sequencing. This procedure identified seven distinct porB sequences, demonstrating variation in the PorB protein recognized by the serotype 22 monoclonal antibody. This is consistent with the genetic heterogeneity of serotype 22 meningococci reported previously.

SUBMITTER: Urwin R 

PROVIDER: S-EPMC105262 | biostudies-literature | 1998 Dec

REPOSITORIES: biostudies-literature

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Heterogeneity of the PorB protein in serotype 22 Neisseria meningitidis.

Urwin R R   Fox A J AJ   Musilek M M   Kriz P P   Maiden M C MC  

Journal of clinical microbiology 19981201 12


The genetic diversity of porB genes from meningococcal isolates characterized as serotype 22 was investigated by gene sequencing. This procedure identified seven distinct porB sequences, demonstrating variation in the PorB protein recognized by the serotype 22 monoclonal antibody. This is consistent with the genetic heterogeneity of serotype 22 meningococci reported previously. ...[more]

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