A naturally occurring novel allele of Escherichia coli outer membrane protein A reduces sensitivity to bacteriophage.
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ABSTRACT:
SUBMITTER: Power ML
PROVIDER: S-EPMC1694255 | biostudies-literature | 2006 Dec
REPOSITORIES: biostudies-literature
Publications
A naturally occurring novel allele of Escherichia coli outer membrane protein A reduces sensitivity to bacteriophage.
Power Michelle L ML Ferrari Belinda C BC Littlefield-Wyer Jane J Gordon David M DM Slade Martin B MB Veal Duncan A DA
Applied and environmental microbiology 20060915 12
A novel Escherichia coli outer membrane protein A (OmpA) was discovered through a proteomic investigation of cell surface proteins. DNA polymorphisms were localized to regions encoding the protein's surface-exposed loops which are known phage receptor sites. Bacteriophage sensitivity testing indicated an association between bacteriophage resistance and isolates having the novel ompA allele. ...[more]
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