Ontology highlight
ABSTRACT:
SUBMITTER: Carballido-Lopez R
PROVIDER: S-EPMC1698507 | biostudies-literature | 2006 Dec
REPOSITORIES: biostudies-literature
Microbiology and molecular biology reviews : MMBR 20061201 4
Recent advances have shown conclusively that bacterial cells possess distant but true homologues of actin (MreB, ParM, and the recently uncovered MamK protein). Despite weak amino acid sequence similarity, MreB and ParM exhibit high structural homology to actin. Just like F-actin in eukaryotes, MreB and ParM assemble into highly dynamic filamentous structures in vivo and in vitro. MreB-like proteins are essential for cell viability and have been implicated in major cellular processes, including ...[more]