Ontology highlight
ABSTRACT:
SUBMITTER: Hastie T
PROVIDER: S-EPMC17599 | biostudies-literature | 2001
REPOSITORIES: biostudies-literature
Hastie T T Tibshirani R R Botstein D D Brown P P
Genome biology 20010110 1
<h4>Background</h4>We propose a new method for supervised learning from gene expression data. We call it 'tree harvesting'. This technique starts with a hierarchical clustering of genes, then models the outcome variable as a sum of the average expression profiles of chosen clusters and their products. It can be applied to many different kinds of outcome measures such as censored survival times, or a response falling in two or more classes (for example, cancer classes). The method can discover ge ...[more]