Ontology highlight
ABSTRACT:
SUBMITTER: Karpanen T
PROVIDER: S-EPMC1764216 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Karpanen Terhi T Wirzenius Maria M Mäkinen Taija T Veikkola Tanja T Haisma Hidde J HJ Achen Marc G MG Stacker Steven A SA Pytowski Bronislaw B Ylä-Herttuala Seppo S Alitalo Kari K
The American journal of pathology 20060801 2
Lymphatic vessel plasticity and stability are of considerable importance when attempting to treat diseases associated with the lymphatic vasculature. Development of lymphatic vessels during embryogenesis is dependent on vascular endothelial growth factor (VEGF)-C but not VEGF-D. Using a recombinant adenovirus encoding a soluble form of their receptor VEGFR-3 (AdVEGFR-3-Ig), we studied lymphatic vessel dependency on VEGF-C and VEGF-D induced VEGFR-3 signaling in postnatal and adult mice. Transduc ...[more]