Ontology highlight
ABSTRACT:
SUBMITTER: Abruzzi K
PROVIDER: S-EPMC1800678 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Molecular and cellular biology 20061113 3
Genetic screens in Saccharomyces cerevisiae provide novel information about interacting genes and pathways. We screened for high-copy-number suppressors of a strain with the gene encoding the nuclear exosome component Rrp6p deleted, with either a traditional plate screen for suppressors of rrp6Delta temperature sensitivity or a novel microarray enhancer/suppressor screening (MES) strategy. MES combines DNA microarray technology with high-copy-number plasmid expression in liquid media. The plate ...[more]