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Effect of carbonates/phosphates as nucleophilic catalysts in dimethylformamide for efficient cyanosilylation of aldehydes and ketones.

ABSTRACT: Cyanosilylation of aldehydes and aliphatic ketones can be carried out in dimethylformamide even without the use of any catalyst. In the presence of nucleophilic catalysts such as carbonate and phosphate salts, the reaction rate is significantly enhanced.

SUBMITTER: Prakash GK

PROVIDER: S-EPMC1805593 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature

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Effect of carbonates/phosphates as nucleophilic catalysts in dimethylformamide for efficient cyanosilylation of aldehydes and ketones.

Prakash G K Surya GK Vaghoo Habiba H Panja Chiradeep C Surampudi Vijayalakshmi V Kultyshev Roman R Mathew Thomas T Olah George A GA

Proceedings of the National Academy of Sciences of the United States of America 20070222 9

Cyanosilylation of aldehydes and aliphatic ketones can be carried out in dimethylformamide even without the use of any catalyst. In the presence of nucleophilic catalysts such as carbonate and phosphate salts, the reaction rate is significantly enhanced. ...[more]

PMID: 17360603

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