A microRNA signature of hypoxia.
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ABSTRACT:
SUBMITTER: Kulshreshtha R
PROVIDER: S-EPMC1820461 | biostudies-literature | 2007 Mar
REPOSITORIES: biostudies-literature
Publications
A microRNA signature of hypoxia.
Kulshreshtha Ritu R Ferracin Manuela M Wojcik Sylwia E SE Garzon Ramiro R Alder Hansjuerg H Agosto-Perez Francisco J FJ Davuluri Ramana R Liu Chang-Gong CG Croce Carlo M CM Negrini Massimo M Calin George A GA Ivan Mircea M
Molecular and cellular biology 20061228 5
Recent research has identified critical roles for microRNAs in a large number of cellular processes, including tumorigenic transformation. While significant progress has been made towards understanding the mechanisms of gene regulation by microRNAs, much less is known about factors affecting the expression of these noncoding transcripts. Here, we demonstrate for the first time a functional link between hypoxia, a well-documented tumor microenvironment factor, and microRNA expression. Microarray- ...[more]
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