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Systematic overestimation of gene gain through false diagnosis of gene absence.


ABSTRACT: The usual BLAST-based methods for assessing gene presence and absence lead to systematic overestimation of within-species gene gain by lateral transfer.

SUBMITTER: Zhaxybayeva O 

PROVIDER: S-EPMC1852405 | biostudies-literature | 2007

REPOSITORIES: biostudies-literature

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Systematic overestimation of gene gain through false diagnosis of gene absence.

Zhaxybayeva Olga O   Nesbø Camilla L CL   Doolittle W Ford WF  

Genome biology 20070101 2


The usual BLAST-based methods for assessing gene presence and absence lead to systematic overestimation of within-species gene gain by lateral transfer. ...[more]

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