Ontology highlight
ABSTRACT:
SUBMITTER: Yu W
PROVIDER: S-EPMC1855040 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Yu Wei W Fang Xiaohui X Ewald Andrew A Wong Kit K Hunt C Anthony CA Werb Zena Z Matthay Michael A MA Mostov Keith K
Molecular biology of the cell 20070301 5
Many organs consist of a hollow cavity surrounded by a monolayer of epithelial cells. Despite their common structure, such organs form by diverse morphogenetic processes. Three-dimensional culture systems have been useful in analyzing the events. Most processes require a combination of cell proliferation and cell death to produce a hollow cavity. Here, we describe a new three-dimensional culture system in which primary human lung alveolar type II cells formed hollow epithelial cysts by a novel p ...[more]