Ontology highlight
ABSTRACT:
SUBMITTER: Schwarz-Romond T
PROVIDER: S-EPMC186448 | biostudies-literature | 2002 Aug
REPOSITORIES: biostudies-literature
Schwarz-Romond Thomas T Asbrand Christian C Bakkers Jeroen J Kühl Michael M Schaeffer Hans-Joerg HJ Huelsken Jörg J Behrens Jürgen J Hammerschmidt Matthias M Birchmeier Walter W
Genes & development 20020801 16
Wnt signals control decisive steps in development and can induce the formation of tumors. Canonical Wnt signals control the formation of the embryonic axis, and are mediated by stabilization and interaction of beta-catenin with Lef/Tcf transcription factors. An alternative branch of the Wnt pathway uses JNK to establish planar cell polarity in Drosophila and gastrulation movements in vertebrates. We describe here the vertebrate protein Diversin that interacts with two components of the canonical ...[more]