Ontology highlight
ABSTRACT:
SUBMITTER: Darieva Z
PROVIDER: S-EPMC1890309 | biostudies-literature | 2006 Nov
REPOSITORIES: biostudies-literature
Darieva Zoulfia Z Bulmer Richard R Pic-Taylor Aline A Doris Kathryn S KS Geymonat Marco M Sedgwick Steven G SG Morgan Brian A BA Sharrocks Andrew D AD
Nature 20061101 7118
Polo kinases have crucial conserved functions in controlling the eukaryotic cell cycle through orchestrating several events during mitosis. An essential element of cell cycle control is exerted by altering the expression of key regulators. Here we show an important function for the polo kinase Cdc5p in controlling cell-cycle-dependent gene expression that is crucial for the execution of mitosis in the model eukaryote Saccharomyces cerevisiae. In particular, we find that Cdc5p is temporally recru ...[more]