Ontology highlight
ABSTRACT:
SUBMITTER: Rao VR
PROVIDER: S-EPMC1891664 | biostudies-literature | 2006 Jan
REPOSITORIES: biostudies-literature
Rao Venkata Rao Dodaghatta Krishna VR Ramanjeneyulu Rallapalli R Rao Dowlathabad Muralidhara DM Kumar Chitta Suresh CS
Bioinformation 20060124 3
Lysyl tRNA synthetases facilitate amino acylation and play a crucial role in the essential cellular process of translation. They are grouped into two distinct classes (class I and class II). Class I lysyl tRNA synthetase is considered as a drug target for syphilis caused by Treponema pallidum. Comparative genome analysis shows the absence of its sequence homolog in eukaryotes. The structure of class I lysyl tRNA synthetase from Treponema pallidum is unknown and the difficulties in the in vitro c ...[more]