Ontology highlight
ABSTRACT:
SUBMITTER: Gruidl ME
PROVIDER: S-EPMC19442 | biostudies-literature | 1996 Nov
REPOSITORIES: biostudies-literature
Gruidl M E ME Smith P A PA Kuznicki K A KA McCrone J S JS Kirchner J J Roussell D L DL Strome S S Bennett K L KL
Proceedings of the National Academy of Sciences of the United States of America 19961101 24
Two components of the germ-line-specific P granules of the nematode Caenorhabditis elgans have been identified using polyclonal antibodies specific for each. Both components are putative germ-line RNA helicases (GLHs) that contain CCHC zinc fingers of the type found in the RNA-binding nucleocapsid proteins of retroviruses. The predicted GLH-1 protein has four CCHC fingers; GLH-2 has six. Both GLH proteins localize in the P granules at all stage of germ-line development. However, the two glh gene ...[more]