Ontology highlight
ABSTRACT:
SUBMITTER: Hughes CL
PROVIDER: S-EPMC1978164 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Hughes Cynthia L CL Thomas John B JB
Molecular and cellular neurosciences 20070406 2
Drosophila larval crawling is a simple behavior that allows us to dissect the functions of specific neurons in the intact animal and explore the roles of genes in the specification of those neurons. By inhibiting subsets of neurons in the PNS, we have found that two classes of multidendritic neurons play a major role in larval crawling. The bipolar dendrites and class I mds send a feedback signal to the CNS that keeps the contraction wave progressing quickly, allowing smooth forward movement. Ge ...[more]