Ontology highlight
ABSTRACT:
SUBMITTER: Lee K
PROVIDER: S-EPMC1995741 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Lee Kiwon K Kang Mi Jin MJ Kwon Su Jin SJ Kwon Yunhee Kim YK Kim Ki Woo KW Lim Jae-Hwan JH Kwon Hyockman H
Molecular biology of the cell 20070725 10
Chromosomes are compartmentalized into discrete chromosome territories during interphase in mammalian cells. A chromosome territory is generated by the tendency of chromatin to occupy the smallest shell volume, which is determined by the polymeric properties and interactions of the internal meshwork of the chromatin fiber. Here, we show that BAF53 knockdown by small interfering RNA interference led to the expansion of chromosome territories. This was accompanied by a reduction in chromatin compa ...[more]