Ontology highlight
ABSTRACT:
SUBMITTER: Brangwynne CP
PROVIDER: S-EPMC2042173 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Brangwynne Clifford P CP MacKintosh F C FC Weitz David A DA
Proceedings of the National Academy of Sciences of the United States of America 20071002 41
Microtubules are highly dynamic biopolymer filaments involved in a wide variety of biological processes including cell division, migration, and intracellular transport. Microtubules are very rigid and form a stiff structural scaffold that resists deformation. However, despite their rigidity, inside of cells they typically exhibit significant bends on all length scales. Here, we investigate the origin of these bends using a Fourier analysis approach to quantify their length and time dependence. W ...[more]