Ontology highlight
ABSTRACT:
SUBMITTER: Shiratori I
PROVIDER: S-EPMC2211832 | biostudies-literature | 2004 Feb
REPOSITORIES: biostudies-literature
The Journal of experimental medicine 20040201 4
Paired receptors that consist of highly related activating and inhibitory receptors are widely involved in the regulation of the immune system. Here, we report a mouse orthologue of the human activating paired immunoglobulin-like type 2 receptor (PILR) beta, which was cloned from a cDNA library of natural killer (NK) cells based on its ability to associate with the DAP12 signaling adaptor protein. The activating PILRbeta was expressed not only on NK cells but also on dendritic cells and macropha ...[more]