Ontology highlight
ABSTRACT:
SUBMITTER: Meunier JC
PROVIDER: S-EPMC2224608 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Meunier Jean-Christophe JC Russell Rodney S RS Goossens Vera V Priem Sofie S Walter Hugo H Depla Erik E Union Ann A Faulk Kristina N KN Bukh Jens J Emerson Suzanne U SU Purcell Robert H RH
Journal of virology 20071031 2
The relative importance of humoral and cellular immunity in the prevention or clearance of hepatitis C virus (HCV) infection is poorly understood. However, there is considerable evidence that neutralizing antibodies are involved in disease control. Here we describe the detailed analysis of human monoclonal antibodies (MAbs) directed against HCV glycoprotein E1, which may have the potential to control HCV infection. We have identified two MAbs that can strongly neutralize HCV-pseudotyped particle ...[more]