Ontology highlight
ABSTRACT:
SUBMITTER: Lin YL
PROVIDER: S-EPMC2268987 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Virus research 20071105 2
Two products of human cytomegalovirus (HCMV) UL111a gene have been previously identified to resemble human IL-10 (hIL-10). These viral IL-10s (vIL-10s) are able to induce signal transduction events and biological activities in a variety of cells. In this study, five novel vIL-10 transcripts were identified from HCMV AD169 infected MRC-5 cells. Some vIL-10 isoforms were post-translationally glycosylated, depending on the existence of a predicted N-linked glycosylation site. Similar to hIL-10, fou ...[more]