Nonautonomous sex determination controls sexually dimorphic development of the Drosophila gonad.
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ABSTRACT:
SUBMITTER: DeFalco T
PROVIDER: S-EPMC2292836 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Publications
Nonautonomous sex determination controls sexually dimorphic development of the Drosophila gonad.
DeFalco Tony T Camara Nicole N Le Bras Stéphanie S Van Doren Mark M
Developmental cell 20080201 2
Sex determination in Drosophila is commonly thought to be a cell-autonomous process, where each cell decides its own sexual fate based on its sex chromosome constitution (XX versus XY). This is in contrast to sex determination in mammals, which largely acts nonautonomously through cell-cell signaling. Here we examine how sexual dimorphism is created in the Drosophila gonad by investigating the formation of the pigment cell precursors, a male-specific cell type in the embryonic gonad. Surprisingl ...[more]
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