Ontology highlight
ABSTRACT:
SUBMITTER: Tsai HH
PROVIDER: S-EPMC2425503 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Tsai Hsiu-Hui HH Huang Chih-Hung CH Lin Alan M AM Chen Carton W CW
Nucleic acids research 20080514 10
Streptomyces species are highly abundant soil bacteria that possess linear chromosomes (and linear plasmids). The 5' ends of these molecules are covalently bound by terminal proteins (TPs), that are important for integrity and replication of the telomeres. There are at least two types of TPs, both of which contain a DNA-binding domain and a classical eukaryotic nuclear localization signal (NLS). Here we show that the NLS motifs on these TPs are highly efficient in targeting the proteins along wi ...[more]