Ontology highlight
ABSTRACT:
SUBMITTER: Murzik U
PROVIDER: S-EPMC2441681 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Murzik Ulrike U Hemmerich Peter P Weidtkamp-Peters Stefanie S Ulbricht Tobias T Bussen Wendy W Hentschel Julia J von Eggeling Ferdinand F Melle Christian C
Molecular biology of the cell 20080507 7
S100A11 is involved in a variety of intracellular activities such as growth regulation and differentiation. To gain more insight into the physiological role of endogenously expressed S100A11, we used a proteomic approach to detect and identify interacting proteins in vivo. Hereby, we were able to detect a specific interaction between S100A11 and Rad54B, which could be confirmed under in vivo conditions. Rad54B, a DNA-dependent ATPase, is described to be involved in recombinational repair of DNA ...[more]