Proteomic analysis of lamellar bodies isolated from rat lungs.
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ABSTRACT:
SUBMITTER: Wang P
PROVIDER: S-EPMC2459160 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Publications
Proteomic analysis of lamellar bodies isolated from rat lungs.
Wang Pengcheng P Chintagari Narendranath Reddy NR Narayanaperumal Jeyaparthasarathy J Ayalew Sahlu S Hartson Steven S Liu Lin L
BMC cell biology 20080624
<h4>Background</h4>Lamellar bodies are lysosome-related secretory granules and store lung surfactant in alveolar type II cells. To better understand the mechanisms of surfactant secretion, we carried out proteomic analyses of lamellar bodies isolated from rat lungs.<h4>Results</h4>With peptide mass fingerprinting by Matrix Assisted Laser Desorption/Ionization - Time of Flight mass spectrometry, 44 proteins were identified with high confidence. These proteins fell into diverse functional categori ...[more]
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