Ontology highlight
ABSTRACT:
SUBMITTER: Klein S
PROVIDER: S-EPMC7846596 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Klein Steffen S Wimmer Benedikt H BH Winter Sophie L SL Kolovou Androniki A Laketa Vibor V Chlanda Petr P
Communications biology 20210129 1
Lamellar bodies (LBs) are surfactant-rich organelles in alveolar cells. LBs disassemble into a lipid-protein network that reduces surface tension and facilitates gas exchange in the alveolar cavity. Current knowledge of LB architecture is predominantly based on electron microscopy studies using disruptive sample preparation methods. We established and validated a post-correlation on-lamella cryo-correlative light and electron microscopy approach for cryo-FIB milled cells to structurally characte ...[more]