Ontology highlight
ABSTRACT:
SUBMITTER: Xing J
PROVIDER: S-EPMC2471876 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Xing Jinchuan J Witherspoon David J DJ Watkins W Scott WS Zhang Yuhua Y Tolpinrud Whitney W Jorde Lynn B LB
Genomics 20080514 1
Linkage disequilibrium (LD) has received much attention recently because of its value in localizing disease-causing genes. Due to the extensive LD between neighboring loci in the human genome, it is believed that a subset of the single nucleotide polymorphisms in a region (tagSNPs) can be selected to capture most of the remaining SNP variants. In this study, we examined LD patterns and HapMap tagSNP transferability in more than 300 individuals. A South Indian sample and an African Mbuti Pygmy po ...[more]