Ontology highlight
ABSTRACT:
SUBMITTER: Magis AT
PROVIDER: S-EPMC2496861 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Magis Andrew T AT Bailey Kate M KM Kurenova Elena V EV Hernández Prada Jose A JA Cance William G WG Ostrov David A DA
Acta crystallographica. Section F, Structural biology and crystallization communications 20080530 Pt 6
X-ray diffraction data from the targeting (FAT) domain of focal adhesion kinase (FAK) were collected from a single crystal that diffracted to 1.99 A resolution and reduced to the primitive orthorhombic lattice. A single molecule was predicted to be present in the asymmetric unit based on the Matthews coefficient. The data were phased using molecular-replacement methods using an existing model of the FAK FAT domain. All structures of human focal adhesion kinase FAT domains solved to date have bee ...[more]