Ontology highlight
ABSTRACT:
SUBMITTER: Anderson DJ
PROVIDER: S-EPMC2528577 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Anderson Daniel J DJ Hetzer Martin W MW
The Journal of cell biology 20080901 5
During mitosis in metazoans, segregated chromosomes become enclosed by the nuclear envelope (NE), a double membrane that is continuous with the endoplasmic reticulum (ER). Recent in vitro data suggest that NE formation occurs by chromatin-mediated reorganization of the tubular ER; however, the basic principles of such a membrane-reshaping process remain uncharacterized. Here, we present a quantitative analysis of nuclear membrane assembly in mammalian cells using time-lapse microscopy. From the ...[more]