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Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum.

ABSTRACT: [reaction: see text] Two new neoclerodane diterpenes, salvinicins A (4) and B (5), were isolated from the dried leaves of Salvia divinorum. The structures of these compounds were elucidated by spectroscopic techniques, including (1)H and (13)C NMR, NOESY, HMQC, and HMBC. The absolute stereochemistry of these compounds was assigned on the basis of single-crystal X-ray crystallographic analysis of salvinicin A (4) and a 3,4-dichlorobenzoate derivative of salvinorin B.

SUBMITTER: Harding WW

PROVIDER: S-EPMC2535573 | biostudies-literature | 2005 Jul

REPOSITORIES: biostudies-literature

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Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum.

Harding Wayne W WW Tidgewell Kevin K Schmidt Matthew M Shah Kushal K Dersch Christina M CM Snyder John J Parrish Damon D Deschamps Jeffrey R JR Rothman Richard B RB Prisinzano Thomas E TE

Organic letters 20050701 14

[reaction: see text] Two new neoclerodane diterpenes, salvinicins A (4) and B (5), were isolated from the dried leaves of Salvia divinorum. The structures of these compounds were elucidated by spectroscopic techniques, including (1)H and (13)C NMR, NOESY, HMQC, and HMBC. The absolute stereochemistry of these compounds was assigned on the basis of single-crystal X-ray crystallographic analysis of salvinicin A (4) and a 3,4-dichlorobenzoate derivative of salvinorin B. ...[more]

PMID: 15987194

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Synthetic studies of neoclerodane diterpenes from Salvia divinorum: exploration of the 1-position.

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Salvia divinorum isolate:xyz

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