Ontology highlight
ABSTRACT:
SUBMITTER: Sonderegger I
PROVIDER: S-EPMC2556786 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Sonderegger Ivo I Iezzi Giandomenica G Maier Reinhard R Schmitz Nicole N Kurrer Michael M Kopf Manfred M
The Journal of experimental medicine 20080908 10
Granulocyte macrophage-colony stimulating factor (GM-CSF) is critically involved in development of organ-related autoimmune inflammatory diseases including experimental allergic encephalitis and collagen-induced arthritis. Roles of GM-CSF in the initiation and in the effector phase of the autoimmune response have been proposed. Our study was designed to investigate the mechanisms of GM-CSF in autoimmunity using a model of autoimmune heart inflammatory disease (myocarditis). The pathological sequ ...[more]