Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen P
PROVIDER: S-EPMC2573239 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Nguyen Phuongmai P Bar-Sela Gil G Sun Lunching L Bisht Kheem S KS Cui Hengmi H Kohn Elise E Feinberg Andrew P AP Gius David D
Molecular and cellular biology 20080902 21
Chromatin status is characterized in part by covalent posttranslational modifications of histones that regulate chromatin dynamics and direct gene expression. BORIS (brother of the regulator of imprinted sites) is an insulator DNA-binding protein that is thought to play a role in chromatin organization and gene expression. BORIS is a cancer-germ line gene; these are genes normally present in male germ cells (testis) that are also expressed in cancer cell lines as well as primary tumors. This wor ...[more]