Ontology highlight
ABSTRACT:
SUBMITTER: Boxem M
PROVIDER: S-EPMC2596478 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Cell 20080801 3
Many protein-protein interactions are mediated through independently folding modular domains. Proteome-wide efforts to model protein-protein interaction or "interactome" networks have largely ignored this modular organization of proteins. We developed an experimental strategy to efficiently identify interaction domains and generated a domain-based interactome network for proteins involved in C. elegans early-embryonic cell divisions. Minimal interacting regions were identified for over 200 prote ...[more]