Ontology highlight
ABSTRACT:
SUBMITTER: Hayakawa J
PROVIDER: S-EPMC2615408 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Hayakawa Jun J Washington Kareem K Uchida Naoya N Phang Oswald O Kang Elizabeth M EM Hsieh Matthew M MM Tisdale John F JF
PloS one 20090116 1
We previously reported the efficacy of nonmyeloablative allogeneic transplantation in 2 HIV positive recipients, one of whom received retrovirus transduced hematopoietic stem cells to confer resistance to HIV. Here we report an assessment of retroviral integration sites (RISs) recovered out to 3 years post-transplantation. We identified 213 unique RISs from the patient's peripheral blood samples by linear amplification-mediated PCR (LAM-PCR). While vector integration patterns were similar to tha ...[more]