Ontology highlight
ABSTRACT:
SUBMITTER: Smith SW
PROVIDER: S-EPMC2626171 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Smith Sean W SW Fu Gregory C GC
Journal of the American Chemical Society 20080903 38
A stereoconvergent method for the catalytic asymmetric Negishi cross-coupling of racemic secondary propargylic halides with arylzinc reagents has been developed. Neither family of compounds has previously been shown to be a suitable partner in such coupling processes. From a practical point of view, it is noteworthy that the catalyst components (NiCl2.glyme and pybox ligand 1) are commercially available. ...[more]