Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC2627835 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Zhang Jian J Tomasini Amber J AJ Mayer Alan N AN
BMC developmental biology 20081216
<h4>Background</h4>RNA-binding motif protein 19 (RBM19, NCBI Accession # NP_083038) is a conserved nucleolar protein containing 6 conserved RNA recognition motifs. Its biochemical function is to process rRNA for ribosome biogenesis, and it has been shown to play a role in digestive organ development in zebrafish. Here we analyzed the role of RBM19 during mouse embryonic development by generating mice containing a mutation in the Rbm19 locus via gene-trap insertion.<h4>Results</h4>Homozygous muta ...[more]