Ontology highlight
ABSTRACT:
SUBMITTER: Zeng W
PROVIDER: S-EPMC2638068 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Zeng Wei W Chemler Sherry R SR
The Journal of organic chemistry 20080628 15
The enantioselective synthesis of (S)-(+)-tylophorine, a potent cancer cell growth inhibitor, has been accomplished in eight steps from commercially available 3,4-dimethoxybenzyl alcohol. A copper (II)-catalyzed enantioselective intramolecular alkene carboamination was employed as the key step to construct the chiral indolizidine ring. ...[more]