Ontology highlight
ABSTRACT:
SUBMITTER: Varnai P
PROVIDER: S-EPMC2644460 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Methods (San Diego, Calif.) 20081016 3
Inositol lipids and calcium signaling has been inseparable twins during the 1980s when the molecular details of phospholipase C-mediated generation of inositol 1,4,5-trisphosphate (InsP3) and its Ca2+ mobilizing action were discovered. Since then, both the Ca2+ and inositol lipid signaling fields have hugely expanded and the tools allowing dissection of the finest details of their molecular organization also followed closely. Although phosphoinositides regulate many cell functions unrelated to C ...[more]