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Resin capsules: permeable containers for parallel/combinatorial solid-phase organic synthesis.

ABSTRACT: A resin capsule is a permeable container for resin beads designed for multiple/combinatorial solid-phase organic synthesis. Resin capsules consist of a high density polyethylene ring sealed with peek mesh on both sides. The cylindrical shape of resin capsules enabled space-saving packing into plastic columnlike reaction vessels commonly used for solid-phase organic synthesis. Resin capsules have been evaluated for their use in combinatorial synthesis, and a set of model compounds with excellent purity was prepared.

SUBMITTER: Bouillon I 

PROVIDER: S-EPMC2652863 | biostudies-literature | 2008 Sep-Oct

REPOSITORIES: biostudies-literature

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Resin capsules: permeable containers for parallel/combinatorial solid-phase organic synthesis.

Bouillon Isabelle I   Soural Miroslav M   Krchnák Viktor V  

Journal of combinatorial chemistry 20080726 5

A resin capsule is a permeable container for resin beads designed for multiple/combinatorial solid-phase organic synthesis. Resin capsules consist of a high density polyethylene ring sealed with peek mesh on both sides. The cylindrical shape of resin capsules enabled space-saving packing into plastic columnlike reaction vessels commonly used for solid-phase organic synthesis. Resin capsules have been evaluated for their use in combinatorial synthesis, and a set of model compounds with excellent  ...[more]

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