Ontology highlight
ABSTRACT:
SUBMITTER: Cosset FL
PROVIDER: S-EPMC2655582 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Cosset François-Loic FL Marianneau Philippe P Verney Geraldine G Gallais Fabrice F Tordo Noel N Pécheur Eve-Isabelle EI ter Meulen Jan J Deubel Vincent V Bartosch Birke B
Journal of virology 20090119 7
The cell entry and humoral immune response of the human pathogen Lassa virus (LV), a biosafety level 4 (BSL4) Old World arenavirus, are not well characterized. LV pseudoparticles (LVpp) are a surrogate model system that has been used to decipher factors and routes involved in LV cell entry under BSL2 conditions. Here, we describe LVpp, which are highly infectious, with titers approaching those obtained with pseudoparticles displaying G protein of vesicular stomatitis virus and their the use for ...[more]