The DNA sequence of the human X chromosome.
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ABSTRACT:
SUBMITTER: Ross MT
PROVIDER: S-EPMC2665286 | biostudies-literature | 2005 Mar
REPOSITORIES: biostudies-literature
Publications
The DNA sequence of the human X chromosome.
Ross Mark T MT Grafham Darren V DV Coffey Alison J AJ Scherer Steven S McLay Kirsten K Muzny Donna D Platzer Matthias M Howell Gareth R GR Burrows Christine C Bird Christine P CP Frankish Adam A Lovell Frances L FL Howe Kevin L KL Ashurst Jennifer L JL Fulton Robert S RS Sudbrak Ralf R Wen Gaiping G Jones Matthew C MC Hurles Matthew E ME Andrews T Daniel TD Scott Carol E CE Searle Stephen S Ramser Juliane J Whittaker Adam A Deadman Rebecca R Carter Nigel P NP Hunt Sarah E SE Chen Rui R Cree Andrew A Gunaratne Preethi P Havlak Paul P Hodgson Anne A Metzker Michael L ML Richards Stephen S Scott Graham G Steffen David D Sodergren Erica E Wheeler David A DA Worley Kim C KC Ainscough Rachael R Ambrose Kerrie D KD Ansari-Lari M Ali MA Aradhya Swaroop S Ashwell Robert I S RI Babbage Anne K AK Bagguley Claire L CL Ballabio Andrea A Banerjee Ruby R Barker Gary E GE Barlow Karen F KF Barrett Ian P IP Bates Karen N KN Beare David M DM Beasley Helen H Beasley Oliver O Beck Alfred A Bethel Graeme G Blechschmidt Karin K Brady Nicola N Bray-Allen Sarah S Bridgeman Anne M AM Brown Andrew J AJ Brown Mary J MJ Bonnin David D Bruford Elspeth A EA Buhay Christian C Burch Paula P Burford Deborah D Burgess Joanne J Burrill Wayne W Burton John J Bye Jackie M JM Carder Carol C Carrel Laura L Chako Joseph J Chapman Joanne C JC Chavez Dean D Chen Ellson E Chen Guan G Chen Yuan Y Chen Zhijian Z Chinault Craig C Ciccodicola Alfredo A Clark Sue Y SY Clarke Graham G Clee Chris M CM Clegg Sheila S Clerc-Blankenburg Kerstin K Clifford Karen K Cobley Vicky V Cole Charlotte G CG Conquer Jen S JS Corby Nicole N Connor Richard E RE David Robert R Davies Joy J Davis Clay C Davis John J Delgado Oliver O Deshazo Denise D Dhami Pawandeep P Ding Yan Y Dinh Huyen H Dodsworth Steve S Draper Heather H Dugan-Rocha Shannon S Dunham Andrew A Dunn Matthew M Durbin K James KJ Dutta Ireena I Eades Tamsin T Ellwood Matthew M Emery-Cohen Alexandra A Errington Helen H Evans Kathryn L KL Faulkner Louisa L Francis Fiona F Frankland John J Fraser Audrey E AE Galgoczy Petra P Gilbert James J Gill Rachel R Glöckner Gernot G Gregory Simon G SG Gribble Susan S Griffiths Coline C Grocock Russell R Gu Yanghong Y Gwilliam Rhian R Hamilton Cerissa C Hart Elizabeth A EA Hawes Alicia A Heath Paul D PD Heitmann Katja K Hennig Steffen S Hernandez Judith J Hinzmann Bernd B Ho Sarah S Hoffs Michael M Howden Phillip J PJ Huckle Elizabeth J EJ Hume Jennifer J Hunt Paul J PJ Hunt Adrienne R AR Isherwood Judith J Jacob Leni L Johnson David D Jones Sally S de Jong Pieter J PJ Joseph Shirin S SS Keenan Stephen S Kelly Susan S Kershaw Joanne K JK Khan Ziad Z Kioschis Petra P Klages Sven S Knights Andrew J AJ Kosiura Anna A Kovar-Smith Christie C Laird Gavin K GK Langford Cordelia C Lawlor Stephanie S Leversha Margaret M Lewis Lora L Liu Wen W Lloyd Christine C Lloyd David M DM Loulseged Hermela H Loveland Jane E JE Lovell Jamieson D JD Lozado Ryan R Lu Jing J Lyne Rachael R Ma Jie J Maheshwari Manjula M Matthews Lucy H LH McDowall Jennifer J McLaren Stuart S McMurray Amanda A Meidl Patrick P Meitinger Thomas T Milne Sarah S Miner George G Mistry Shailesh L SL Morgan Margaret M Morris Sidney S Müller Ines I Mullikin James C JC Nguyen Ngoc N Nordsiek Gabriele G Nyakatura Gerald G O'Dell Christopher N CN Okwuonu Geoffery G Palmer Sophie S Pandian Richard R Parker David D Parrish Julia J Pasternak Shiran S Patel Dina D Pearce Alex V AV Pearson Danita M DM Pelan Sarah E SE Perez Lesette L Porter Keith M KM Ramsey Yvonne Y Reichwald Kathrin K Rhodes Susan S Ridler Kerry A KA Schlessinger David D Schueler Mary G MG Sehra Harminder K HK Shaw-Smith Charles C Shen Hua H Sheridan Elizabeth M EM Shownkeen Ratna R Skuce Carl D CD Smith Michelle L ML Sotheran Elizabeth C EC Steingruber Helen E HE Steward Charles A CA Storey Roy R Swann R Mark RM Swarbreck David D Tabor Paul E PE Taudien Stefan S Taylor Tineace T Teague Brian B Thomas Karen K Thorpe Andrea A Timms Kirsten K Tracey Alan A Trevanion Steve S Tromans Anthony C AC d'Urso Michele M Verduzco Daniel D Villasana Donna D Waldron Lenee L Wall Melanie M Wang Qiaoyan Q Warren James J Warry Georgina L GL Wei Xuehong X West Anthony A Whitehead Siobhan L SL Whiteley Mathew N MN Wilkinson Jane E JE Willey David L DL Williams Gabrielle G Williams Leanne L Williamson Angela A Williamson Helen H Wilming Laurens L Woodmansey Rebecca L RL Wray Paul W PW Yen Jennifer J Zhang Jingkun J Zhou Jianling J Zoghbi Huda H Zorilla Sara S Buck David D Reinhardt Richard R Poustka Annemarie A Rosenthal André A Lehrach Hans H Meindl Alfons A Minx Patrick J PJ Hillier Ladeana W LW Willard Huntington F HF Wilson Richard K RK Waterston Robert H RH Rice Catherine M CM Vaudin Mark M Coulson Alan A Nelson David L DL Weinstock George G Sulston John E JE Durbin Richard R Hubbard Tim T Gibbs Richard A RA Beck Stephan S Rogers Jane J Bentley David R DR
Nature 20050301 7031
The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the X chromosome. Our analysis illustrates the autosomal origin of the mammalian sex chromosomes, the stepwise process that led to the progressive loss of recombination between X and Y, and the extent of subsequent degradation of the Y chromosome. LINE1 repeat elements cover one-third of the X chromosome, with a di ...[more]