Ontology highlight
ABSTRACT:
SUBMITTER: Skucas E
PROVIDER: S-EPMC2676672 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20090401 14
Ruthenium-catalyzed transfer hydrogenation of N-sulfonamido allene 1e in the presence of aromatic aldehydes 2a-f, alpha,beta-unsaturated aldehydes 2g-i, and aliphatic aldehydes 2j-l results in reductive coupling to furnish the corresponding anti-aminoallylation products 3a-l. Reductive coupling of allenamide 1e to aldehyde 2a conducted using 2-propanol-d(8) as the terminal reductant delivers deuterio-3a. The observed pattern of deuterium incorporation suggests reversible allene hydrometalation w ...[more]