Ontology highlight
ABSTRACT:
SUBMITTER: Mottier-Pavie V
PROVIDER: S-EPMC2682601 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Mottier-Pavie Violaine V Megraw Timothy L TL
Molecular biology of the cell 20090325 10
Cilia and flagella play multiple essential roles in animal development and cell physiology. Defective cilium assembly or motility represents the etiological basis for a growing number of human diseases. Therefore, how cilia and flagella assemble and the processes that drive motility are essential for understanding these diseases. Here we show that Drosophila Bld10, the ortholog of Chlamydomonas reinhardtii Bld10p and human Cep135, is a ubiquitous centriolar protein that also localizes to the spe ...[more]