Ontology highlight
ABSTRACT:
SUBMITTER: Vatakis DN
PROVIDER: S-EPMC2687367 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Vatakis Dimitrios N DN Kim Sanggu S Kim Namshin N Chow Samson A SA Zack Jerome A JA
Journal of virology 20090415 12
Until very recently, quiescent CD4(+) T cells were thought to be resistant to human immunodeficiency virus (HIV) infection. Subsequent studies, attempting to fully elucidate the mechanisms of resistance, showed that quiescent cells could become infected by HIV at low efficiency and form a latently infected population. In this study, we set out to identify the sites of viral integration and to assess the efficiency of the overall integration process in quiescent cells. Based on our results, HIV i ...[more]