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TFCat: the curated catalog of mouse and human transcription factors.


ABSTRACT: Unravelling regulatory programs governed by transcription factors (TFs) is fundamental to understanding biological systems. TFCat is a catalog of mouse and human TFs based on a reliable core collection of annotations obtained by expert review of the scientific literature. The collection, including proven and homology-based candidate TFs, is annotated within a function-based taxonomy and DNA-binding proteins are organized within a classification system. All data and user-feedback mechanisms are available at the TFCat portal (http://www.tfcat.ca).

SUBMITTER: Fulton DL 

PROVIDER: S-EPMC2691000 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature

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TFCat: the curated catalog of mouse and human transcription factors.

Fulton Debra L DL   Sundararajan Saravanan S   Badis Gwenael G   Hughes Timothy R TR   Wasserman Wyeth W WW   Roach Jared C JC   Sladek Rob R  

Genome biology 20090312 3


Unravelling regulatory programs governed by transcription factors (TFs) is fundamental to understanding biological systems. TFCat is a catalog of mouse and human TFs based on a reliable core collection of annotations obtained by expert review of the scientific literature. The collection, including proven and homology-based candidate TFs, is annotated within a function-based taxonomy and DNA-binding proteins are organized within a classification system. All data and user-feedback mechanisms are a  ...[more]

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