Detection of breast cancer microcalcifications using a dual-modality SPECT/NIR fluorescent probe.
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ABSTRACT:
SUBMITTER: Bhushan KR
PROVIDER: S-EPMC2696399 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Publications
Detection of breast cancer microcalcifications using a dual-modality SPECT/NIR fluorescent probe.
Bhushan Kumar R KR Misra Preeti P Liu Fangbing F Mathur Sanjeev S Lenkinski Robert E RE Frangioni John V JV
Journal of the American Chemical Society 20081201 52
Efficient chemical synthesis of a trifunctional, hydroxyapatite-binding molecule, which provides simultaneous in vivo imaging by NIR fluorescence and SPECT/CT has been described. Quantitation by SPECT provides the "gold standard" by which NIR fluorescence tomography of breast cancer microcalcifications can now be compared and optimized. ...[more]
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