Unknown

Dataset Information

0

Efficient traceless solid-phase synthesis of 3,4-dihydropyrazino[1,2-b]indazoles and their 6-oxides.


ABSTRACT: A highly efficient novel traceless solid-phase synthesis of 3,4-dihydropyrazino[1,2-b]indazoles and their 6-oxides was developed by using commercially available building blocks, diamines, 2-nitrobenzenesulfonyl chlorides, and bromoketones/bromoacetates. Mild reaction conditions, diversely substituted building blocks, and high purity of crude products enabled effective combinatorial syntheses of libraries.

SUBMITTER: Pudelova N 

PROVIDER: S-EPMC2703815 | biostudies-literature | 2009 May-Jun

REPOSITORIES: biostudies-literature

altmetric image

Publications

Efficient traceless solid-phase synthesis of 3,4-dihydropyrazino[1,2-b]indazoles and their 6-oxides.

Pudelová Nadezda N   Krchnák Viktor V  

Journal of combinatorial chemistry 20090501 3


A highly efficient novel traceless solid-phase synthesis of 3,4-dihydropyrazino[1,2-b]indazoles and their 6-oxides was developed by using commercially available building blocks, diamines, 2-nitrobenzenesulfonyl chlorides, and bromoketones/bromoacetates. Mild reaction conditions, diversely substituted building blocks, and high purity of crude products enabled effective combinatorial syntheses of libraries. ...[more]

Similar Datasets

| S-EPMC2811364 | biostudies-literature
| S-EPMC6102595 | biostudies-literature
| S-EPMC5125624 | biostudies-literature
| S-EPMC8693395 | biostudies-literature
| S-EPMC2653199 | biostudies-literature
| S-EPMC2598405 | biostudies-literature
| S-EPMC9016848 | biostudies-literature
| S-EPMC6479686 | biostudies-literature
| S-EPMC397399 | biostudies-other
| S-EPMC6273450 | biostudies-literature