Ontology highlight
ABSTRACT:
SUBMITTER: Yu Z
PROVIDER: S-EPMC2711180 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Yu Zhengquan Z Mannik Jaana J Soto Amelia A Lin Kevin K KK Lin Kevin K KK Andersen Bogi B
The EMBO journal 20090604 13
Skin and bladder epithelia form effective permeability barriers through the activation of distinct differentiation gene programs. Using a genome-wide gene-expression study, we identified transcriptional regulators whose expression correlates highly with that of differentiation markers in both the bladder and skin, including the Grainyhead factor Get1/Grhl3, which is already known to be important for epidermal barrier formation. In the bladder, Get1 is most highly expressed in the differentiated ...[more]